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A transgenic approach for RNA interference-based genetic screening in mice

Genetic screening is the most powerful method through which to uncover gene function. It has been applied very successfully in lower organisms but seldom attempted in mammalian species because of their long generation time. In this study, we exploit RNA interference (RNAi) for its potential use in g...

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Detalhes bibliográficos
Main Authors: Peng, Shaohua, York, J. Philippe, Zhang, Pumin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413752/
https://ncbi.nlm.nih.gov/pubmed/16461920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511034103
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