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Cre-lox-regulated conditional RNA interference from transgenes

We have generated two lentiviral vectors for conditional, Cre-lox-regulated, RNA interference. One vector allows for conditional activation, whereas the other permits conditional inactivation of short hairpin RNA (shRNA) expression. The former is based on a strategy in which the mouse U6 promoter ha...

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Detalles Bibliográficos
Main Authors: Ventura, Andrea, Meissner, Alexander, Dillon, Christopher P., McManus, Michael, Sharp, Phillip A., Van Parijs, Luk, Jaenisch, Rudolf, Jacks, Tyler
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC478580/
https://ncbi.nlm.nih.gov/pubmed/15240889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403954101
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