Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication

A series of nonnucleoside, N-α-methylbenzyl-N′-arylthiourea analogs were identified which demonstrated selective activity against varicella-zoster virus (VZV) but were inactive against other human herpesviruses, including herpes simplex virus. Representative compounds had potent activity against VZV...

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Autori principali: Visalli, Robert J., Fairhurst, Jeanette, Srinivas, Shamala, Hu, William, Feld, Boris, DiGrandi, Martin, Curran, Kevin, Ross, Adma, Bloom, Jonathan D., van Zeijl, Marja, Jones, Thomas R., O'Connell, John, Cohen, Jeffrey I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC141108/
https://ncbi.nlm.nih.gov/pubmed/12551972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2349-2358.2003
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