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Specific Inhibition of Human Cytomegalovirus Glycoprotein B-Mediated Fusion by a Novel Thiourea Small Molecule

A novel small molecule inhibitor of human cytomegalovirus (HCMV) was identified as the result of screening a chemical library by using a whole-virus infected-cell assay. Synthetic chemistry efforts yielded the analog designated CFI02, a compound whose potency had been increased about 100-fold over a...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Jones, Thomas R., Lee, Shi-Wu, Johann, Stephen V., Razinkov, Vladimir, Visalli, Robert J., Feld, Boris, Bloom, Jonathan D., O'Connell, John
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321382/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14722284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.3.1289-1300.2004
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