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Antiviral Activity of a Small-Molecule Inhibitor of Arenavirus Glycoprotein Processing by the Cellular Site 1 Protease

Arenaviruses merit interest as clinically important human pathogens and include several causative agents, chiefly Lassa virus (LASV), of hemorrhagic fever disease in humans. There are no licensed LASV vaccines, and current antiarenavirus therapy is limited to the use of ribavirin, which is only part...

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Detalhes bibliográficos
Main Authors: Urata, Shuzo, Yun, Nadezhda, Pasquato, Antonella, Paessler, Slobodan, Kunz, Stefan, de la Torre, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020022/
https://ncbi.nlm.nih.gov/pubmed/21068251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02019-10
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