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Antiviral Activity of a Small-Molecule Inhibitor of Arenavirus Glycoprotein Processing by the Cellular Site 1 Protease

Arenaviruses merit interest as clinically important human pathogens and include several causative agents, chiefly Lassa virus (LASV), of hemorrhagic fever disease in humans. There are no licensed LASV vaccines, and current antiarenavirus therapy is limited to the use of ribavirin, which is only part...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Urata, Shuzo, Yun, Nadezhda, Pasquato, Antonella, Paessler, Slobodan, Kunz, Stefan, de la Torre, Juan Carlos
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020022/
https://ncbi.nlm.nih.gov/pubmed/21068251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02019-10
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