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Molecular Characterization of the Processing of Arenavirus Envelope Glycoprotein Precursors by Subtilisin Kexin Isozyme-1/Site-1 Protease

A crucial step in the life cycle of arenaviruses is the biosynthesis of the mature fusion-active viral envelope glycoprotein (GP) that is essential for virus-host cell attachment and entry. The maturation of the arenavirus GP precursor (GPC) critically depends on proteolytic processing by the cellul...

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Détails bibliographiques
Auteurs principaux: Burri, Dominique J., Pasqual, Giulia, Rochat, Cylia, Seidah, Nabil G., Pasquato, Antonella, Kunz, Stefan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347368/
https://ncbi.nlm.nih.gov/pubmed/22357276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00024-12
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