Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242

The cellular protease subtilisin kexin isozyme-1 (SKI-1)/site-1 protease (S1P) is implicated in the proteolytic processing of the viral envelope glycoprotein precursor (GPC) of arenaviruses, a step strictly required for production of infectious progeny. The small molecule SKI-1/S1P inhibitor PF-4292...

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Bibliografiset tiedot
Päätekijät: Pasquato, Antonella, Rochat, Cylia, Burri, Dominique J., Pasqual, Giulia, de la Torre, Juan Carlos, Kunz, Stefan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285533/
https://ncbi.nlm.nih.gov/pubmed/22154237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.11.008
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