Zymogen Activation and Subcellular Activity of Subtilisin Kexin Isozyme 1/Site 1 Protease

The proprotein convertase subtilisin kexin isozyme 1 (SKI-1)/site 1 protease (S1P) plays crucial roles in cellular homeostatic functions and is hijacked by pathogenic viruses for the processing of their envelope glycoproteins. Zymogen activation of SKI-1/S1P involves sequential autocatalytic process...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: da Palma, Joel Ramos, Burri, Dominique Julien, Oppliger, Joël, Salamina, Marco, Cendron, Laura, de Laureto, Patrizia Polverino, Seidah, Nabil Georges, Kunz, Stefan, Pasquato, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276844/
https://ncbi.nlm.nih.gov/pubmed/25378398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588525
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