Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication

A series of nonnucleoside, N-α-methylbenzyl-N′-arylthiourea analogs were identified which demonstrated selective activity against varicella-zoster virus (VZV) but were inactive against other human herpesviruses, including herpes simplex virus. Representative compounds had potent activity against VZV...

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Bibliographische Detailangaben
Hauptverfasser: Visalli, Robert J., Fairhurst, Jeanette, Srinivas, Shamala, Hu, William, Feld, Boris, DiGrandi, Martin, Curran, Kevin, Ross, Adma, Bloom, Jonathan D., van Zeijl, Marja, Jones, Thomas R., O'Connell, John, Cohen, Jeffrey I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141108/
https://ncbi.nlm.nih.gov/pubmed/12551972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2349-2358.2003
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