Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication

A series of nonnucleoside, N-α-methylbenzyl-N′-arylthiourea analogs were identified which demonstrated selective activity against varicella-zoster virus (VZV) but were inactive against other human herpesviruses, including herpes simplex virus. Representative compounds had potent activity against VZV...

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Autors principals: Visalli, Robert J., Fairhurst, Jeanette, Srinivas, Shamala, Hu, William, Feld, Boris, DiGrandi, Martin, Curran, Kevin, Ross, Adma, Bloom, Jonathan D., van Zeijl, Marja, Jones, Thomas R., O'Connell, John, Cohen, Jeffrey I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC141108/
https://ncbi.nlm.nih.gov/pubmed/12551972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2349-2358.2003
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