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Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication

A series of nonnucleoside, N-α-methylbenzyl-N′-arylthiourea analogs were identified which demonstrated selective activity against varicella-zoster virus (VZV) but were inactive against other human herpesviruses, including herpes simplex virus. Representative compounds had potent activity against VZV...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Visalli, Robert J., Fairhurst, Jeanette, Srinivas, Shamala, Hu, William, Feld, Boris, DiGrandi, Martin, Curran, Kevin, Ross, Adma, Bloom, Jonathan D., van Zeijl, Marja, Jones, Thomas R., O'Connell, John, Cohen, Jeffrey I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141108/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12551972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.4.2349-2358.2003
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