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Identification of Small Molecule Compounds That Selectively Inhibit Varicella-Zoster Virus Replication

A series of nonnucleoside, N-α-methylbenzyl-N′-arylthiourea analogs were identified which demonstrated selective activity against varicella-zoster virus (VZV) but were inactive against other human herpesviruses, including herpes simplex virus. Representative compounds had potent activity against VZV...

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Bibliografiske detaljer
Main Authors: Visalli, Robert J., Fairhurst, Jeanette, Srinivas, Shamala, Hu, William, Feld, Boris, DiGrandi, Martin, Curran, Kevin, Ross, Adma, Bloom, Jonathan D., van Zeijl, Marja, Jones, Thomas R., O'Connell, John, Cohen, Jeffrey I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC141108/
https://ncbi.nlm.nih.gov/pubmed/12551972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.4.2349-2358.2003
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