The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity

Older age is associated with increased infectious morbidity and decreased immune responses to vaccines, but the mechanisms that mediate this effect are incompletely understood. The efficacy and immunogenicity of the live attenuated zoster vaccine (ZVL) have a very-well-described negative association...

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Vydáno v:J Virol
Hlavní autoři: Weinberg, Adriana, Pang, Lei, Johnson, Michael J., Caldas, Yupanqui, Cho, Alice, Tovar-Salazar, Adriana, Canniff, Jennifer, Schmader, Kenneth E., Popmihajlov, Zoran, Levin, Myron J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639287/
https://ncbi.nlm.nih.gov/pubmed/31092579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00305-19
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