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The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity

Older age is associated with increased infectious morbidity and decreased immune responses to vaccines, but the mechanisms that mediate this effect are incompletely understood. The efficacy and immunogenicity of the live attenuated zoster vaccine (ZVL) have a very-well-described negative association...

詳細記述

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書誌詳細
出版年:J Virol
主要な著者: Weinberg, Adriana, Pang, Lei, Johnson, Michael J., Caldas, Yupanqui, Cho, Alice, Tovar-Salazar, Adriana, Canniff, Jennifer, Schmader, Kenneth E., Popmihajlov, Zoran, Levin, Myron J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639287/
https://ncbi.nlm.nih.gov/pubmed/31092579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00305-19
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