The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity

Older age is associated with increased infectious morbidity and decreased immune responses to vaccines, but the mechanisms that mediate this effect are incompletely understood. The efficacy and immunogenicity of the live attenuated zoster vaccine (ZVL) have a very-well-described negative association...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Weinberg, Adriana, Pang, Lei, Johnson, Michael J., Caldas, Yupanqui, Cho, Alice, Tovar-Salazar, Adriana, Canniff, Jennifer, Schmader, Kenneth E., Popmihajlov, Zoran, Levin, Myron J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639287/
https://ncbi.nlm.nih.gov/pubmed/31092579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00305-19
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