Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Vascular endothelial growth factor (VEGF) signaling is critical to the processes of angiogenesis and tumor growth. Here, evidence is presented for VEGF stimulation of sphingosine kinase (SPK) that affects not only endothelial cell signaling but also tumor cells expressing VEGF receptors. VEGF or pho...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Shu, Xiaodong, Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.22.7758-7768.2002
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