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Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Vascular endothelial growth factor (VEGF) signaling is critical to the processes of angiogenesis and tumor growth. Here, evidence is presented for VEGF stimulation of sphingosine kinase (SPK) that affects not only endothelial cell signaling but also tumor cells expressing VEGF receptors. VEGF or pho...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Shu, Xiaodong, Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.22.7758-7768.2002
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