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Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Vascular endothelial growth factor (VEGF) signaling is critical to the processes of angiogenesis and tumor growth. Here, evidence is presented for VEGF stimulation of sphingosine kinase (SPK) that affects not only endothelial cell signaling but also tumor cells expressing VEGF receptors. VEGF or pho...

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Publicat a:Mol Cell Biol
Autors principals: Shu, Xiaodong, Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.22.7758-7768.2002
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