Ultrasensitivity in the mitogen-activated protein kinase cascade.

The mitogen-activated protein kinase (MAPK) cascade is a highly conserved series of three protein kinases implicated in diverse biological processes. Here we demonstrate that the cascade arrangement has unexpected consequences for the dynamics of MAPK signaling. We solved the rate equations for the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Huang, C Y, Ferrell, J E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10078
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