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Cellular N-Ras Promotes Cell Survival by Downregulation of Jun N-Terminal Protein Kinase and p38

Cellular N-Ras provides a steady-state antiapoptotic signal, at least partially through the regulation of phosphorylated Akt and Bad levels. Fibroblasts lacking c-N-Ras expression are highly sensitive to the induction of apoptosis by a variety of agents. Reduction of pBad and pAkt levels using a pho...

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Pubblicato in:Mol Cell Biol
Autori principali: Wolfman, Janice C., Palmby, Todd, Der, Channing J., Wolfman, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11839824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.22.5.1589-1606.2002
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