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Interaction of Rac Exchange Factors Tiam1 and Ras-GRF1 with a Scaffold for the p38 Mitogen-Activated Protein Kinase Cascade
Tiam1 and Ras-GRF1 are guanine nucleotide exchange factors (GEFs) that activate the Rac GTPase. The two GEFs have similar N-terminal regions containing pleckstrin homology domains followed by coiled-coils and additional sequences that function together to allow regulated GEF activity. Here we show t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2002
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133864/ https://ncbi.nlm.nih.gov/pubmed/12024021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4073-4085.2002 |
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