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Interaction of Rac Exchange Factors Tiam1 and Ras-GRF1 with a Scaffold for the p38 Mitogen-Activated Protein Kinase Cascade

Tiam1 and Ras-GRF1 are guanine nucleotide exchange factors (GEFs) that activate the Rac GTPase. The two GEFs have similar N-terminal regions containing pleckstrin homology domains followed by coiled-coils and additional sequences that function together to allow regulated GEF activity. Here we show t...

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Autors principals: Buchsbaum, Rachel J., Connolly, Beth A., Feig, Larry A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC133864/
https://ncbi.nlm.nih.gov/pubmed/12024021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4073-4085.2002
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