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Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Vascular endothelial growth factor (VEGF) signaling is critical to the processes of angiogenesis and tumor growth. Here, evidence is presented for VEGF stimulation of sphingosine kinase (SPK) that affects not only endothelial cell signaling but also tumor cells expressing VEGF receptors. VEGF or pho...

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Publicado en:Mol Cell Biol
Autores principales: Shu, Xiaodong, Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134718/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.22.7758-7768.2002
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