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Sphingosine Kinase Mediates Vascular Endothelial Growth Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases

Vascular endothelial growth factor (VEGF) signaling is critical to the processes of angiogenesis and tumor growth. Here, evidence is presented for VEGF stimulation of sphingosine kinase (SPK) that affects not only endothelial cell signaling but also tumor cells expressing VEGF receptors. VEGF or pho...

詳細記述

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書誌詳細
主要な著者: Shu, Xiaodong, Wu, Weicheng, Mosteller, Raymond D., Broek, Daniel
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC134718/
https://ncbi.nlm.nih.gov/pubmed/12391145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.22.7758-7768.2002
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