The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

Lignende værker

• Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGE
  af: Heikaus, Clemens C., et al.
  Udgivet: (2008)
• The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change
  af: Martinez, Sergio E., et al.
  Udgivet: (2008)
• Structural Analysis of the Regulatory GAF Domains of cGMP Phosphodiesterase Elucidates the Allosteric Communication Pathway
  af: Gupta, Richa, et al.
  Udgivet: (2020)
• Conformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain
  af: Wang, Huanchen, et al.
  Udgivet: (2010)
• cGMP inhibition of heart phosphodiesterase: is it clinically relevant?
  af: Beavo, J A
  Udgivet: (1995)