लोड हो रहा है...
The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding
Cyclic nucleotide phosphodiesterases (PDEs) regulate all pathways that use cGMP or cAMP as a second messenger. Five of the 11 PDE families have regulatory segments containing GAF domains, 3 of which are known to bind cGMP. In PDE2 binding of cGMP to the GAF domain causes an activation of the catalyt...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The National Academy of Sciences
2002
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC130621/ https://ncbi.nlm.nih.gov/pubmed/12271124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192374899 |
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