The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change

Gelijkaardige items

• Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: INSIGHTS INTO NUCLEOTIDE SPECIFICITY, DIMERIZATION, AND cGMP-DEPENDENT CONFORMATIONAL CHANGE
  door: Heikaus, Clemens C., et al.
  Gepubliceerd in: (2008)
• The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding
  door: Martinez, Sergio E., et al.
  Gepubliceerd in: (2002)
• Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases.
  door: Charbonneau, H, et al.
  Gepubliceerd in: (1990)
• Cyclic Nucleotide Binding GAF Domains from Phosphodiesterases – Structural and Mechanistic Insights
  door: Heikaus, Clemens C., et al.
  Gepubliceerd in: (2009)
• Conformation Changes, N-terminal Involvement, and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain
  door: Wang, Huanchen, et al.
  Gepubliceerd in: (2010)