Загрузка...
Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding
Previous structural studies on native T5 5′ nuclease, a member of the flap endonuclease family of structure-specific nucleases, demonstrated that this enzyme possesses an unusual helical arch mounted on the enzyme's active site. Based on this structure, the protein's surface charge distrib...
Сохранить в:
| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2002
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124304/ https://ncbi.nlm.nih.gov/pubmed/12084915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082241699 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|