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Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease
On the basis of structural work, metal ions are proposed to play a catalytic role in reactions mediated by many phosphoryl transfer enzymes. To gain dynamic support for such mechanisms, the role of metal ion cofactors in phosphate diester hydrolysis catalysed by a flap endonuclease has been studied....
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150332/ https://ncbi.nlm.nih.gov/pubmed/12606565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg098 |
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