Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease

Flap endonucleases (FENs) catalyse the exonucleolytic hydrolysis of blunt-ended duplex DNA substrates and the endonucleolytic cleavage of 5′-bifurcated nucleic acids at the junction formed between single- and double-stranded DNA. The specificity and catalytic parameters of FENs derived from T5 bacte...

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Bibliografiske detaljer
Main Authors: Williams, Ryan, Sengerová, Blanka, Osborne, Sadie, Syson, Karl, Ault, Sophie, Kilgour, Anna, Chapados, Brian R, Tainer, John A, Sayers, Jon R, Grasby, Jane A
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993357/
https://ncbi.nlm.nih.gov/pubmed/17559871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.04.063
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