The structure of Escherichia coli ExoIX—implications for DNA binding and catalysis in flap endonucleases

Escherichia coli Exonuclease IX (ExoIX), encoded by the xni gene, was the first identified member of a novel subfamily of ubiquitous flap endonucleases (FENs), which possess only one of the two catalytic metal-binding sites characteristic of other FENs. We have solved the first structure of one of t...

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Autors principals: Anstey-Gilbert, Christopher S., Hemsworth, Glyn R., Flemming, Claudia S., Hodskinson, Michael R. G., Zhang, Jing, Sedelnikova, Svetlana E., Stillman, Timothy J., Sayers, Jon R., Artymiuk, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783174/
https://ncbi.nlm.nih.gov/pubmed/23821668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt591
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