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Active site substitutions delineate distinct classes of eubacterial flap endonuclease
FENs (flap endonucleases) play essential roles in DNA replication, pivotally in the resolution of Okazaki fragments. In eubacteria, DNA PolI (polymerase I) contains a flap processing domain, the N-terminal 5′→3′ exonuclease. We present evidence of paralogous FEN-encoding genes present in many eubact...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650880/ https://ncbi.nlm.nih.gov/pubmed/19000038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081637 |
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