Antibody probe study of Ca2+ channel regulation by interdomain interaction within the ryanodine receptor.

N-terminal and central domains of ryanodine receptor 1 (RyR1), where many reported malignant hyperthermia (MH) mutations are localized, represent putative channel regulatory domains. Recent domain peptide (DP) probe studies led us to the hypothesis that these domains interact to stabilize the closed...

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Detalhes bibliográficos
Main Authors: Kobayashi, Shigeki, Yamamoto, Takeshi, Parness, Jerome, Ikemoto, Noriaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224195/
https://ncbi.nlm.nih.gov/pubmed/15027895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040112
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