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Antibody probe study of Ca2+ channel regulation by interdomain interaction within the ryanodine receptor.

N-terminal and central domains of ryanodine receptor 1 (RyR1), where many reported malignant hyperthermia (MH) mutations are localized, represent putative channel regulatory domains. Recent domain peptide (DP) probe studies led us to the hypothesis that these domains interact to stabilize the closed...

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Bibliografske podrobnosti
Main Authors: Kobayashi, Shigeki, Yamamoto, Takeshi, Parness, Jerome, Ikemoto, Noriaki
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224195/
https://ncbi.nlm.nih.gov/pubmed/15027895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040112
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