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Postulated role of interdomain interaction between regions 1 and 2 within type 1 ryanodine receptor in the pathogenesis of porcine malignant hyperthermia

We have demonstrated recently that CICR (Ca(2+)-induced Ca(2+) release) activity of RyR1 (ryanodine receptor 1) is held to a low level in mammalian skeletal muscle (‘suppression’ of the channel) and that this is largely caused by the interdomain interaction within RyR1 [Murayama, Oba, Kobayashi, Ike...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Murayama, Takashi, Oba, Toshiharu, Hara, Hiroshi, Wakebe, Kikuo, Ikemoto, Noriaki, Ogawa, Yasuo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Portland Press Ltd. 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798429/
https://ncbi.nlm.nih.gov/pubmed/17107340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061040
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