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High-throughput kinase assays with protein substrates using fluorescent polymer superquenching

BACKGROUND: High-throughput screening is used by the pharmaceutical industry for identifying lead compounds that interact with targets of pharmacological interest. Because of the key role that aberrant regulation of protein phosphorylation plays in diseases such as cancer, diabetes and hypertension,...

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Bibliografski detalji
Glavni autori: Rininsland, Frauke, Stankewicz, Casey, Weatherford, Wendy, McBranch, Duncan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166542/
https://ncbi.nlm.nih.gov/pubmed/15927069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-16
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