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A real-time high-throughput fluorescence assay for sphingosine kinases

Sphingosine kinases (SphKs), of which there are two isoforms, SphK1 and SphK2, have been implicated in regulation of many important cellular processes. We have developed an assay for monitoring SphK1 and SphK2 activity in real time without the need for organic partitioning of products, radioactive m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lima, Santiago, Milstien, Sheldon, Spiegel, Sarah
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076073/
https://ncbi.nlm.nih.gov/pubmed/24792926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D048132
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