Fluorescent-conjugated polymer superquenching facilitates highly sensitive detection of proteases

Sensor formats have been developed for detecting the activity of proteolytic enzymes based on fluorescent conjugated polymer superquenching. These sensors employ a reactive peptide sequence within a tether linking a quencher to a biotin. The peptide binds to sensors containing colocated biotin-bindi...

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Main Authors: Kumaraswamy, Sriram, Bergstedt, Troy, Shi, Xiaobo, Rininsland, Frauke, Kushon, Stuart, Xia, Wensheng, Ley, Kevin, Achyuthan, Komandoor, McBranch, Duncan, Whitten, David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Physical Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC419636/
https://ncbi.nlm.nih.gov/pubmed/15136731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402367101
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