Fluorescent-conjugated polymer superquenching facilitates highly sensitive detection of proteases

Sensor formats have been developed for detecting the activity of proteolytic enzymes based on fluorescent conjugated polymer superquenching. These sensors employ a reactive peptide sequence within a tether linking a quencher to a biotin. The peptide binds to sensors containing colocated biotin-bindi...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kumaraswamy, Sriram, Bergstedt, Troy, Shi, Xiaobo, Rininsland, Frauke, Kushon, Stuart, Xia, Wensheng, Ley, Kevin, Achyuthan, Komandoor, McBranch, Duncan, Whitten, David
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
Materias:
Physical Sciences
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15136731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402367101
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