High-throughput kinase assays with protein substrates using fluorescent polymer superquenching

BACKGROUND: High-throughput screening is used by the pharmaceutical industry for identifying lead compounds that interact with targets of pharmacological interest. Because of the key role that aberrant regulation of protein phosphorylation plays in diseases such as cancer, diabetes and hypertension,...

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Detaylı Bibliyografya
Asıl Yazarlar: Rininsland, Frauke, Stankewicz, Casey, Weatherford, Wendy, McBranch, Duncan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2005
Konular:
Methodology Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166542/
https://ncbi.nlm.nih.gov/pubmed/15927069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-16
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