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High-throughput kinase assays with protein substrates using fluorescent polymer superquenching
BACKGROUND: High-throughput screening is used by the pharmaceutical industry for identifying lead compounds that interact with targets of pharmacological interest. Because of the key role that aberrant regulation of protein phosphorylation plays in diseases such as cancer, diabetes and hypertension,...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1166542/ https://ncbi.nlm.nih.gov/pubmed/15927069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-16 |
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