The Survival of Motor Neurons Protein Determines the Capacity for snRNP Assembly: Biochemical Deficiency in Spinal Muscular Atrophy

Reduction of the survival of motor neurons (SMN) protein levels causes the motor neuron degenerative disease spinal muscular atrophy, the severity of which correlates with the extent of reduction in SMN. SMN, together with Gemins 2 to 7, forms a complex that functions in the assembly of small nuclea...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Wan, Lili, Battle, Daniel J., Yong, Jeongsik, Gubitz, Amelie K., Kolb, Stephen J., Wang, Jin, Dreyfuss, Gideon
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Gene Expression
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156985/
https://ncbi.nlm.nih.gov/pubmed/15964810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5543-5551.2005
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы