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Spinal Muscular Atrophy: From Defective Chaperoning of snRNP Assembly to Neuromuscular Dysfunction

Spinal Muscular Atrophy (SMA) is a neuromuscular disorder that results from decreased levels of the survival motor neuron (SMN) protein. SMN is part of a multiprotein complex that also includes Gemins 2–8 and Unrip. The SMN-Gemins complex cooperates with the protein arginine methyltransferase 5 (PRM...

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Bibliografiska uppgifter
I publikationen:Front Mol Biosci
Huvudupphovsmän: Lanfranco, Maia, Vassallo, Neville, Cauchi, Ruben J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463183/
https://ncbi.nlm.nih.gov/pubmed/28642865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2017.00041
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