The Survival of Motor Neurons Protein Determines the Capacity for snRNP Assembly: Biochemical Deficiency in Spinal Muscular Atrophy

Reduction of the survival of motor neurons (SMN) protein levels causes the motor neuron degenerative disease spinal muscular atrophy, the severity of which correlates with the extent of reduction in SMN. SMN, together with Gemins 2 to 7, forms a complex that functions in the assembly of small nuclea...

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Detaylı Bibliyografya
Asıl Yazarlar: Wan, Lili, Battle, Daniel J., Yong, Jeongsik, Gubitz, Amelie K., Kolb, Stephen J., Wang, Jin, Dreyfuss, Gideon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2005
Konular:
Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156985/
https://ncbi.nlm.nih.gov/pubmed/15964810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5543-5551.2005
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