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snRNAs Contain Specific SMN-Binding Domains That Are Essential for snRNP Assembly

To serve in its function as an assembly machine for spliceosomal small nuclear ribonucleoprotein particles (snRNPs), the survival of motor neurons (SMN) protein complex binds directly to the Sm proteins and the U snRNAs. A specific domain unique to U1 snRNA, stem-loop 1 (SL1), is required for SMN co...

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Detalhes bibliográficos
Main Authors: Yong, Jeongsik, Golembe, Tracey J., Battle, Daniel J., Pellizzoni, Livio, Dreyfuss, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371136/
https://ncbi.nlm.nih.gov/pubmed/15024064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2747-2756.2004
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