snRNAs Contain Specific SMN-Binding Domains That Are Essential for snRNP Assembly

To serve in its function as an assembly machine for spliceosomal small nuclear ribonucleoprotein particles (snRNPs), the survival of motor neurons (SMN) protein complex binds directly to the Sm proteins and the U snRNAs. A specific domain unique to U1 snRNA, stem-loop 1 (SL1), is required for SMN co...

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Bibliographic Details
Main Authors: Yong, Jeongsik, Golembe, Tracey J., Battle, Daniel J., Pellizzoni, Livio, Dreyfuss, Gideon
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC371136/
https://ncbi.nlm.nih.gov/pubmed/15024064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2747-2756.2004
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