Plasminogen-Binding Activity of Neuraminidase Determines the Pathogenicity of Influenza A Virus
When expressed in vitro, the neuraminidase (NA) of A/WSN/33 (WSN) virus binds and sequesters plasminogen on the cell surface, leading to enhanced cleavage of the viral hemagglutinin. To obtain direct evidence that the plasminogen-binding activity of the NA enhances the pathogenicity of WSN virus, we...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11533192/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.19.9297-9301.2001 |
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