Amino Acid Residues Contributing to the Substrate Specificity of the Influenza A Virus Neuraminidase

Influenza A viruses possess two glycoprotein spikes on the virion surface: hemagglutinin (HA), which binds to oligosaccharides containing terminal sialic acid, and neuraminidase (NA), which removes terminal sialic acid from oligosaccharides. Hence, the interplay between these receptor-binding and re...

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Detalhes bibliográficos
Main Authors: Kobasa, Darwyn, Kodihalli, Shantha, Luo, Ming, Castrucci, Maria R., Donatelli, Isabella, Suzuki, Yasuo, Suzuki, Takashi, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112759/
https://ncbi.nlm.nih.gov/pubmed/10400772
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