Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum

Cells expressing ricin B chain within the secretory pathway are significantly more resistant to intoxication by ricin holotoxin but not to other cytotoxins that exploit similar endocytic routes to the cytosol. Furthermore, cells expressing the related B chain of abrin are protected against both inco...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Spooner, Robert A., Watson, Peter D., Marsden, Catherine J., Smith, Daniel C., Moore, Katherine A. H., Cook, Jonathon P., Lord, J. Michael, Roberts, Lynne M.
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2004
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134069/
https://ncbi.nlm.nih.gov/pubmed/15225124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040742
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires