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Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum
Cells expressing ricin B chain within the secretory pathway are significantly more resistant to intoxication by ricin holotoxin but not to other cytotoxins that exploit similar endocytic routes to the cytosol. Furthermore, cells expressing the related B chain of abrin are protected against both inco...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134069/ https://ncbi.nlm.nih.gov/pubmed/15225124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040742 |
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