Ricin A chain without its partner B chain is degraded after retrotranslocation from the endoplasmic reticulum to the cytosol in plant cells

When expressed in tobacco cells, the catalytic subunit of the dimeric ribosome inactivating protein, ricin, is first inserted into the endoplasmic reticulum (ER) and then degraded in a manner that can be partially inhibited by the proteasome inhibitor clasto-lactacystin β-lactone. Consistent with th...

Full description

Saved in:
Bibliographic Details
Main Authors: Di Cola, Alessandra, Frigerio, Lorenzo, Lord, J. Michael, Ceriotti, Aldo, Roberts, Lynne M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC64749/
https://ncbi.nlm.nih.gov/pubmed/11734657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251386098
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items