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Ricin A chain without its partner B chain is degraded after retrotranslocation from the endoplasmic reticulum to the cytosol in plant cells

When expressed in tobacco cells, the catalytic subunit of the dimeric ribosome inactivating protein, ricin, is first inserted into the endoplasmic reticulum (ER) and then degraded in a manner that can be partially inhibited by the proteasome inhibitor clasto-lactacystin β-lactone. Consistent with th...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Di Cola, Alessandra, Frigerio, Lorenzo, Lord, J. Michael, Ceriotti, Aldo, Roberts, Lynne M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11734657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251386098
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